At first 'Perthville' was known as Queen Charlotte's Vale - after Queen Charlotte's Vale Creek which runs alongside Vale Road. Vale Road originally carried heavy traffic in laden bullock and horse drays and the settlement began to cater for the bullockies and coach travellers.
It was proclaimed a village in 1855 and named 'Perth'.
However, in 1908, to avoid confusion with Perth in Western Australia it was re-named as Perthville.
After the proclamation in 1815 of Bathurst as a town, settlement spread south some 12kms to what is now known as Perthville and Georges Plains. There are a number of early colonial buildings in this area.
Perthville is also where the Mother House of the Sisters of St Joseph of the Bathurst Diocese (Perthville Josephites) is situated.
The Perthville Josephites follow in the footsteps of their co-founders Mary MacKillop and Julian Woods, ministering in a variety of ways across the Bathurst Diocese and beyond. Perthville, linked as it is to the life of Blessed Mary MacKillop, is today a pilgrimage site and Josephite centre.
Georges Plains is a quaint village nestled beside the Queen Charlotte's Vale Creek, surrounded by grazing country some 3.5 km down Vale Road from Perthville.
Brian Booth a former Australian Test cricketer (played 29 Tests 1961 - 1966 and captained Australia for 2 Tests 1965 -1966 whilst standing in for Bob Simpson) - was born in Perthville. He represented Bathurst High School at the age of 13 and by the age of 15 played first grade cricket in Bathurst. He made his first class debut for New South Wales in the 1954 -1955 season.